Neuroscientists toward understanding how the brain works – Brain Mapping

Neuroscientists toward understanding how the brain works has made great strides in recent years . U.S. initiative brain will try to create a comprehensive picture of brain activity while in the coming years , Europe’s Human Brain Project , a computational simulation of the human brain will try to make . These ambitious projects would greatly benefit from a new resource : detailed and comprehensive map of the brain ‘s structure and its various regions . As part of the Human Brain Project , German and Canadian scientists led an international team of researchers in the last 50 times the resolution of such a map is a three- dimensional atlas of the brain were produced . Which took a decade to complete atlas , slicing a brain in thousands of thin sections and digitally stitch them back together with the help of supercomputers is required .

As small as 20 micrometers, about the size of several human cells is able to show the details , the brain anatomy.To three-dimensional digital reconstruction of the brain is a major step forward in understanding the guide , Jülich Research Center Katrin Amunts researchers led by a 65- year-old woman in Germany at the start of an MRI machine used for post-mortem brain image . The brain was then cut into ultrathin slices . Scientists stained sections one by one on a flatbed scanner and then imaged. Alan Evans and his colleagues at the Montreal Neurological Institute, a terabyte in size , resulting in about 7,404 images organized in a data set . Evans had to overcome these defects in images so that slicing , bent, torn , and the tissue was torn. They also combine in the brain, each one in its original condition . The result is mesmerizing : the arrangement of cells and tissues to check you out or zooming, a brain model that can swim through .

In the early 20th century , Korbinian Brodmann , a German neuroanatomist sections of the brain under a microscope, looking at the structure and organization of the human cortex into 50 different areas parceled. ” That’s what we ‘ve used that for 100 years has been very much the model structure , ” says Evans . As they map the boundaries between brain areas Brodmann now he and his colleagues are redoing work . Results for the study of various brain functions , providing scientists with a more accurate road map , more like 100 to 200 may show different areas . Amunts nerve fibers in the brain tissue to reconstruct the three-dimensional structure that uses polarized light which is developing a technology . And Karl Deisseroth, a bioengineer at Stanford University , a neuroscientist and developed in the laboratory technique called clarity , scientists directly intact neurons in brain circuitry and allows for viewing of the structures . Because the fat cells in your brain to block light , like any other tissue , is usually opaque . Clarity leaves intact and visible to other structures, replacing them with a gel-like substance , lipid melts away . Clarity can be used on a whole mouse brain , human brain technology completely intact with the current version is too large to be studied . But Deisseroth technology already is easier and less error prone 3d reconstruction , a thin brain, human brain tissue section thousands of times larger than can be used to block calls .